Porcessed rehmannia root is often used in conditions like lumbar and knee weakness, hot flush, bone pain, night sweats, spermatic emission, diabetic symptoms, sallow complex, palpitations, irregular menses, excessive menses, dizziness, ear ringing, and premature graying.^[2],[3]

• Processed rehmannia root is a commonly used blood tonic
  For anemia or blood deficient conditions, processed rehmannia root can work with angelica root, white peony root, and Sichuan lovage rhizome (the Four-substance Decoction) to promote blood production. When the patients also have qi (vital energy) deficiency that accompanies with mental fatigue and general weakness, ginseng should be added to the remedy. Otherwise, the Four-substance Decoction will combine with pilose asiabell root, largehead atractylodes rhizome, poria and liquorice root to formulate as the Eight-treasure Decoction for replenishing both blood and qi. In case of serious anemia or blood deficiency, the remedy may also be added fleeceflower root, donkey-hide gelatin, and suberect spatholobus stem.
• Porcessed rehmannia root is commonly used for women health problems
  Blood deficiency leads to scanty menses or irregular periods, processed rehmannia root can work with angelica root, white peony root, Sichuan lovage rhizome, bupleurum root and nutgrass flatsedge rhizome for relief. Long term heavy menses flow will lead to blood and yin deficiencies, which can be treated with the herb along with dried rehmannia root, angelica root, white peony root, donkey-hide gelatin, and tortoise shell glue. Processed rehmannia root along with angelica root, himalayan teasel root, mulberry mistletoes, largehead atractylodes rhizome and baical skullcap root can relieve stirring fetus in pregnant women. Blood deficiency or blood stasis in postnatal women will develop abdominal pain, which can be treated by processed rehmannia root along with angelica root, Sichuan lovage rhizome, and cassia bark.
• Processed rehmannia root is an important ingredient for yin nourishment
  Weakness due to yin deficiency often accompanied with hot flush, night sweats, lumbar soreness, seminal emission, throat dryness, thirst, a red tongue tip and the pulse is rapid and thready. Processed rehmannia root is often used along with cornus fruit, Chinese yam, poria, peony root bark, and oriental water-plantain rhizome to formulate as the Six-ingredient Rehmannia Decoction for relief. In case if the virtual fire symptoms are serious, anemarrhena rhizome, amur corktree bark and tortoise shell will be added to clear the fire. Clinically, modern TCM discovered that conditions like hypertension, diabetes, chronic nephritis, and nervous breakdown tend to have the above situations, and thus the Six-ingredient Rehmannia Decoction is often selected and modified for appropriate conditions.
• Processed rehmannia root replenishes kidney essence and recovers marrow storage
  Growth retardation in children, or early degeneration and gray hair in middle-aged people are associated with insufficiency of essence and marrow, processed rehmannia root can work with fleeceflower root, glossy privet fruit, wolfberry fruit and tortoise shell glue for improvement. For asthmatic symptoms that associated with kidney deficiency, processed rehmannia root can be selected along with achyranthes root, angelica root, cassia bark and roasted liquorice root. In case of urinary frequency or incontinence, the herb can work with dodder seed, cherokee rose fruit, and palmleaf raspberry fruit to invigorate kidney system and enhance bladder functioning. Chronic diarrhea is often associated with weakness of spleen and kidney, which can be treated by processed rehmannia root along with largehead atractylodes rhizome, Chinese yam and psoralea. A productive cough can be due to kidney weakness that causes excessive dampness and phlegm accumulated inside the body. Processed rehmannia root together with angelica root, pinellia tuber and tangerine peel are selected to dissolve the pathogens and invigorate organ functioning.
• Processed rehmannia root nourishes blood, warms up meridians, expels coldness and unblocks stagnations
  Processed rehmannia root along with deerhorn glue, cassia bark and ephedra can treat serious infections or chronic inflammations. Modern TCM like to apply the herbal combination to treat conditions like chronic abscesses deep inside the body, Buerger disease, tuberculosis conditions and chronic osteomyelitis.

Studies showed that processed rehmannia root has effects in immune regulation, promoting adrenal cortex and sex glands functioning, stimulating bone marrow, enhancing blood coagulation process, improving kidney and heart functioning, diuresis, lowering blood pressure, inhibiting gastric secretions, anti-tumor, inhibiting epithelial cell proliferation, anti-oxidative and anti-aging.^[4],[5]