The diagnosis of contact dermatitis depends on a careful medical history, the distribution of the lesions, and patch-testing. Reactions may appear suddenly, or they may present as a chronic, low-grade, smoldering dermatitis. Possible exposures in the home, work, and recreational environment to potential allergens need to be monitored.
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Skin patch-testing |
The diagnosis is confirmed by patch-testing, a time-honored, well-standardized procedure that is both a test of the skin's immunity and a provocation test that reproduces the disease "in miniature". In the patch test, a suspected contact dermatitis sensitizing agent is applied to normal skin (usually on the upper back) and covered. The patches are removed after 48 hours and the underlying skin examined, with a repeat examination after a further two days. In a positive response, there is inflammation and hardening of skin at the test site. Although there are pitfalls in interpretation, patch-testing is indispensable in the investigation of allergic contact dermatitis.
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