Chrysanthemum tends to clear heat in the upper body, however it is not strong enough to do this alone. For conditions like common cold, upper respiratory infection, pharyngitis, and tonsillitis that are categorized as external invasion of wind and heat in TCM, chrysanthemum is usually combined with mulberry leaf, weeping forsythia capsule, peppermint and platycodon root for relieving fever, headache and coughing coughing.

Yang is generally referred to functional aspect of objects, a hyperactive liver yang means the liver has overplayed its regulatory role in the body, which causes symptoms like headache and dizziness. Chrysanthemum can work with abalone shell, nacre, and white peony root for relief. When situation has further aggravated that leads to liver fire attacking the head, or excessive heat in the liver meridian, chrysanthemum can work with buffalo horn and gambir vine stem to relieve symptoms like headache, dizziness and muscle spasm.

Red eyes is usually associated with wind-heat in the liver meridian or liver fire attacking the head, chrysanthemum can work with cicada slough, horsetail, and silkworm for dispersing wind-heat in the liver meridian; or it can work with abalone shell, cassia seed and selfheal fruit spike for clearing liver fire. Sometimes, blurred vision is due to liver and kidney deficiencies, chrysanthemum can work with wolfberry fruit, processed rhemannia rhizome and cornus fruit to enhance the liver and kidney functioning.

Skin sores and abscess are regarded as toxic heat signs in TCM, chrysanthemum can be used with honeysuckle flower and liquorice root for relief. The herbs can either be decocted for oral administration or ground for external application.

According to the China Food and Drug Administration, chrysanthemum is categorized as a TCM herb and also a healthy food, thus it is a common ingredient in medicinal diets and herbal supplements.