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Asthma : Treatment
   
Western Medicine
Chinese Medicine

The goals for treating asthma are:

1. Prevent symptoms that are bothersome.
2. Maintain normal or near normal lung function.
3. Maintain normal activities and exercise.
4. Provide drug therapy if needed and minimize side effects.
5. Prevent exacerbations and hospitalizations.
6. Make sure the expectations of people with asthma and their families are met.

Drug (Pharmacologic) Therapy:
Understanding how medications work and why they are prescribed are essential for successful asthma management. There are several groups of medication used to treat asthma which are briefly described below.

Medications used for quick relief of asthma symptoms:
1. Short-acting beta2-agonists: These medications are used for quick relief of asthma symptoms and for exercise induced asthma (i.e. albuterol or Proventila or Ventolina).
2. Anticholinergics: This medication is usually given together the beta2 -agonists for severe episodes or given to people who cannot tolerate beta2-agonists (i.e. ipratropium bromide or Atroventa).
3. Systemic corticosteroids: These medications are used in moderate to severe asthma exacerbations to speed recovery. They are often given together with beta2 agonists (i.e. methylprednisolone, prednisone and prednisolone).

Medications used for long-term control of asthma:
1. Corticosteroids: These are the most effective and potent of the anti -inflammatory medications. They are usually inhaled when sued long-term to minimize side-effects but can be given as tablets or even injections during a serious acute episode of asthma (i.e. beclomethasone diproprionate, budesonide, & flunisolide).
2. Cromolyn sodium and nedocromil: These are mild to moderate anti-inflammatory medications often used in children because of their minimal side effects. They may also be used before exercise to prevent wheezing. People continually exposed to allergens also benefit from using them.
3. Leukotriene Modifiers: These are relatively new medications used in the treatment of mild to moderate asthma in teenagers and adults. They are used as alternatives to corticosteroids or cromolyn sodium and nedocromil (i.e. zafirlukast, zileuton or montelukast: approved for children).
4. Methylxanthines: These have a mild to moderate bronchodilator effect and help clear lung secretions. They are usually used together with inhaled corticosteroids to control nighttime asthma symptoms ( i.e. sustained release theophylline).
5. Long-acting beta2 agonists: These medications are usually used with inhaled corticosteroids to gain long-term control of asthma symptoms, especially nighttime symptoms. This type of medication should never be used to treat a sudden onset of asthma symptoms or to treat an asthma attack (i.e. salmeterol).

Note: All of these medications have potential side effects that need to be monitored by your healthcare provider. People with asthma need to know what their medications are treating and be able to recognize potential side effects.

What to do during an asthma attack:
1. EARLY TREATMENT is the BEST.
2. Recognize the symptoms of an attack: increasing cough, wheeze and breathlessness.
3. Always carry medications needed for quick treatment as well as a written plan stating how to recognize an attack, what medications should be started, how frequently they should be given and who to call for help.
4. Seek medical care early if the attack is severe, if the medications do not provide quick relief or sustained improvement, and/ or the symptoms get worse.
5. Make sure you always have the right medications and equipment needed at home to start treatment.

Other Considerations:
Underlying conditions such as rhinitis, sinusitis and gastroesophageal reflux should be treated as they can exacerbate asthma symptoms.
People with aspirin or NSAID sensitivities should avoid taking these drugs and check all medications for these ingredients. People with severe asthma or nasal polyps should also be aware of the potential of these drugs to cause an asthma attack.
Some people are allergic to sulfites, which are used to preserve foods and beverages. Sulfites can trigger an asthma attack and foods such as processed potatoes, wine, beer, dried fruit, and others containing sulfites should be avoided.
Nonselective beta-blockers are used as heart medications and are also used in certain eye solutions. People with asthma should be aware these medications might cause asthma attacks and avoid using them. Discuss alternatives with your healthcare provider.
Allergen immunotherapy (allergy shots) may be effective for some people. This may be needed when a person has repeated exposure to an allergen they cannot avoid, has asthma symptoms for a major portion of the year, or has symptoms that are difficult to control.
Yearly flu shots are recommended for people with asthma because viral infections can worsen asthma symptoms, especially in young children.

SPECIAL AGE CONSIDERATIONS:
Infants & Children under 5 years old:
In this age group it can be difficult to diagnose asthma due to challenges in obtaining reliable lung function testing. Underdiagnosis of asthma still remains a significant problem in this age group. Children are often labeled as having frequent viral infections, chronic bronchitis, wheezy bronchitis, or gastro-oesophageal reflux. When this happens these children often do not receive adequate therapy to relieve their symptoms. It has been estimated between 50-80% of children who have asthma will experience symptoms before the age of five. Most commonly asthma symptoms will present with a viral infection in this age group. Your healthcare provider may prescribe a trial of asthma medications to see if symptoms improve and use a stepwise approach to either escalate or decrease therapy.


School Age Children & Adolescents:
Adolescents and younger children, when mature enough, should be included in developing a plan to manage their asthma. Adolescents, especially, may not understand the significant health risks they are taking when their asthma is poorly controlled. In addition, it may be difficult to accept asthma as a chronic illness at a time when they are developing independence from their family. Fostering a positive self-image and encouraging personal responsibility for managing asthma are necessary.
The healthcare provider and parents should provide the school with an asthma plan that explains the medications the student is taking and what to do in case of an asthma attack.
Children with asthma should not be discouraged from physical exercise and sports. The child may need to take medication before and/or during a physical activity. Limiting physical activity should only be used as a last resort.

Older Adults:
Older adults may have other conditions such as chronic bronchitis or emphysema that cause asthma symptoms. In this case, the symptoms may not be reversible . Therefore, it is important to assess whether medications really can help relieve asthma symptoms.
Asthma medications can be absorbed and metabolized differently in elderly people causing an increase in unwanted side effects. The healthcare provider should monitor these people carefully for side effects or reactions to other medications and make adjustments where appropriate.

SPECIAL SITUATIONS:
Surgery:
People with asthma undergoing surgery should see the healthcare provider managing their asthma before going ahead with the operation. Every attempt should be made to have the best possible lung function before going ahead with a procedure. The healthcare provider may need to increase or change medications before or after the surgery.

Pregnancy:
The overall goal is to maintain adequate lung function so that the fetus can get an adequate oxygen supply. If asthma is not treated sufficiently during pregnancy it can increase the baby's risk of perinatal mortality, prematurity or a low birth weight.
Most of the common asthma medications will not put the fetus at increased risk.
Medications that do pose a risk to the fetus include: epinephrine, brompheniramine, and alpha-adrenergic medications. Medications that have potential risks to the fetus include decongestants, antibiotics, live virus vaccines, immunotherapy (allergy shots), and iodides.
People with asthma should discuss all their medications with their healthcare provider and eliminate or change those likely to pose a risk to the baby.


 

The TCM treatment strategy for asthma is based on the diagnosed disharmony patterns.

Cold type asthma
This type of asthma is caused by the cold evils, the therapeutic aim is to remove the cold evils by warming the lungs. In addition, this decoction helps remove the phlegm and relieve the wheezing.

Decoction examples:
Shegan mahuang decoction

She gan (Blackberrylily Rhizome)
Ma huang (Ephedra)
Gan Jiang (Zingibier or dried ginger)
Xi xin (Manchurian Wild Ginger)
Ban xia (Pinella Tuber)
Zi wan (Tartarian Aster Root)
Kuan dong hua (Common Coltsfoot Flower)
Gan cao (Liquorice Root)
Wu wei zi (Chinese Magnoliavine Fruit)
Da zao (Chinese Date)

In this decoction, She gan and ma huang are responsible for relieving the cough and wheeze, easing the throat and removing the phlegm. Gan jiang, xi xin and ban xia warm the cold phlegm in the lung and reverse the movement of qi. Zi wan, kwuan dong hua and gan cao relieve the cough and remove the phlegm. Wu wei zi stops the lung qi from traveling in the wrong direction and relieves the cough. Da zao helps support the normal qi in the body.

Other related patterns
Wind-Cold tightens the lungs
Wind-cold is an exterior syndrome because it is a pernicious evil which attacks the body from the outside first. The therapeutic goal is to relieve this exterior syndrome with herbs, which are pungent in flavor and warm in property. This helps the lungs to resume their dissemination of qi and provides relief of the asthma symptoms.

Decoction Example
Modified powder of huagai

Ma huang (Ephedra)
Xing ren (Bitter Apricot Seed)
Gan cao (Liquorice Root)
Su zi (Perilla Fruit)
San bai pi (White Mulberry root-bark)
Chen pi (Dried Tangerine Peel)

Heat type asthma
Because this type of asthma is caused by heat evils, the therapeutic goal is to clear away the heat and resume the dissemination of lung qi. Treatment will also remove phlegm and relieve coughing.

Decoction Example
Ding chuan decoction

Ma huang (Ephedra)
Huang qin (Baical Skullcap Root)
San bai pi (White Mulberry Root-Bark)
Xing ren (Bitter Apricot Seed)
Ban xia (Pinella Tuber)
Kuan dong hua (Common Coltsfoot Flower)
Su zi (Perilla Fruit)
Bai guo (Ginkgo Seed)
Gan cao (Liquorice Root)

In this decoction, ma huang restores the lungs' ability to disseminate qi. Huang qin and san bai pi clear away the heat in the lung and restore the liquefying function of the lungs. Xin ren, ban xia, kuan dong and su zi remove the phlegm and redirect qi's movement to descend. Bai guo arrests lung qi. Gan cao keeps the other herbs in balance and supports the body's normal qi.

Other related patterns
Heat retention in lungs
The therapeutic aim is to clear away lung heat and remove phlegm.

Decoction Examples
Maxing shigan decoction with modification

Ma huang (Ephedra)
Xing ren (Bitter Apricot Seed)
Shi gao (Gypsum)
Gan cao (Liquorice Root)
San bai pi (White Mulberry Root-Bark)
Huang qin (Baical Skullcap Root)
Chuan Bei mu (Tendrilleaf Fritillary Bulb)

Stagnation of phlegm dampness in middle warmer (spleen and stomach)
The therapeutic goal to expel the phlegm and support the qi descending function of the lungs. This decoction also helps relieve wheezing.

Example decoction
Daotan decoction combined with sanzi yangqin decoction

Dan nan xing (Bile Arisaema)
Zhi shi (Immature Orange Fruit)
Ban xia (Pinella Tuber)
Chen pi (Dried Tangerine Peel)
Fu ling (Indian Bread or Poiria)
Gan cao (Liquorice Root)
Bai jie zi (Mustard Seed)
Su zi (Perilla Fruit)
Lai fu zi (Radish Seed)

Lung Deficiency
The lungs are responsible for governing the health of protective qi, which is part of our immunity. When lung disharmony occurs the aim is to restore normal lung function and consolidate the exterior and protective qi in the body so illness can be avoided

Decoction examples
Yu ping feng powder

Huang qi (Milkvetch Root or Astragalus)
Bai zhu (Largehead Atractylodes Rhizome)
Fang feng (Divaricate Saposhnikovia Root)

In this decoction, huang qi and bai zhu support qi and consolidate the exterior. Fang feng also helps support exterior consolidation and in addition removes wind evils. Wind evils usually attack the lungs when the exterior of the body is weak.

Shengmai decoction and erchen decoction with modifications

Ren shen (Panax Ginseng)
Mai dong (Dwarf Lilyturf Tuber)
Wu wei zi (Chinese Magnoliavine Fruit)
Huang qi (Milkvetch Root or Astragalus)
Ban xia (Pinella Tuber)
Ju hong (Red Tangerine Peel)
Fu ling (Indian Bread or Poiria)
Gan cao (Liquorice Root)
Zi wan (Tartarian Aster Root)

This is another example of a decoction used to restore lung function.

Spleen Deficiency
The spleen is responsible for transforming fluids into substances that are essential to maintain health. Therefore, in order to restore the healthy balance of the spleen, it is necessary to support the spleen's transformation function and remove the excess unhealthy fluids known as phlegm.

Decoction example
Liu junzi decoction

Dang shen (Tangshen or Radix Codonopsis)
Bai zhu (Largehead Atractylodes Rhizome)
Fu ling (Indian Bread or Poiria)
Gan cao (Liquorice Root)
Chen pi (Dried Tangerine Peel)
Ban xia (Pinella Tuber)

In this decoction, dang shen, bai zhu, fu lin and gan zao are excellent combination herbs for strengthening the spleen and replenishing qi. Chen pi and ban xia are good for removing phlegm and regulating qi. All the herbs in this combination work together to support the spleen's transformation function.

Kidney Deficiency
The kidneys also play an important role in regulating healthy breathing. Therefore, the treatment goal is to replenish the kidneys and support their qi grasping function so healthy breathing can be resumed.

Decoction example
Jingui shengqi pill

Di huang(dry) or sheng di (Rehmannia Root)
Shan zhu yu (Asiatic Cornelian Cherry Fruit)
Shan yao (Common Yam Rhizome)
Fu ling (Indian Bread or Poiria)
Ze xie (Oriental Waterplantain Rhizome)
Mu dan pi (Tree Peony Bark)
Gui zhi (Cassia Twig)
Fu zi (Prepared Common Monkshod Daughter Root)

This is a famous decoction for supporting kidney yang. Di huang is good herb for nourishing the kidney yin. It is usually supported by sha zhu yu and shan yao which enhance the spleen's functions. As di huang has certain wet properties, ze xie is added to remove the excessive fluids and regulate the fluid channels. Fu lin helps support the spleen and transform fluids. Dan pi releases and clears away liver fire resulting from deficient heat. After this, fu zi and gui zhi are added to support the kidney yang. Fu zi helps replenish the yang and dispels the cold while gui zhi warms the meridian so there can be smooth movement of fluids inside the blood vessels.

Other related patterns
Yin difficiency of lungs and kidneys
The therapeutic aim is to nourish the yin and keep the yang in its original place without overwhelming other organs.

Decoction example
Liuwei dihuang decoction combined with shengmai decoction

Sheng dior di huang (Rehmannia Root)
Shan zhu yu (Asiatic Cornelian Cherry Fruit)
Shan yao (Common Yam Rhizome)
Mu dan pi (Tree Peony Bark)
Fu ling (Indian Bread or Poiria)
Ze xie (Oriental Waterplantain Rhizome)
Tai zi shen (Heterophylly Falsestarwort root)
Mai dong (Dwarf Lilyturf Tuber)
Wu wei zi (Chinese Magnoliavine Fruit)